I-Quercetin HPLC98% ejwayelekile yekhwalithi ye-USP40

Nansi eminye imibiko yakamuva yocwaningo mayelana nokusetshenziswa kwe-quercetin

1.I-Quercetin Ithuthukisa Isibindi Esinamafutha: Ngomhla ziyi-19 kuJulayi, 2024, ithimba labacwaningi abavela e-Army Medical University lashicilela impumelelo yocwaningo ku-American Journal of Clinical Nutrition. Benza isilingo somtholampilo esingahleliwe, esiphindwe kabili - esiyimpumputhe, se-placebo - esilawulwa yi-crossover esibandakanya iziguli ze-41 ezine-non-alcoholic fatty disease (NAFLD). Iziguli zathatha amamiligremu angama-500 e-quercetin noma i-placebo nsuku zonke amasonto ayi-12, bese amaqembu amabili eshintsha izindlela zokungenelela amanye amasonto ayi-12. Imiphumela yabonisa ukuthi okuqukethwe kwamafutha esibindi ezigulini zeqembu le-quercetin kwehle kakhulu, ngokuncipha okumaphakathi kwe-17.4%, kuyilapho lokho eqenjini le-placebo kwehle kuphela ngo-0.9%. Phakathi naleso sikhathi, isisindo somzimba kanye ne-BMI yeziguli eziseqenjini le-quercetin nazo zehla kakhulu. Ngaphezu kwalokho, ukuncipha kokuqukethwe kwamafutha esibindi ezigulini zesifazane kwakucishe kube kabili kuneziguli zesilisa. Ayikho imiphumela emibi ye-quercetin ohlelweni lwegazi, ukusebenza kwezinso, nomfutho wegazi wabahlanganyeli owabonwa ngesikhathi socwaningo.

2.I-Quercetin Yehlisa Ukukhuluphala: Ngomhla zingama-31 kuJanuwari, 2025, ithimba labacwaningi eliholwa u-Wang Xinxia wase-Zhejiang University lishicilele isihloko esithi "Quercetin - Driven Akkermansia Muciniphila Aleviates Obesity by Modulating Bile Acid Metabolism via an ILA/m6A/CYP8B1 Signaling" ku-Adv 1 Sci4. Ucwaningo luthole ukuthi i-quercetin - eqhutshwa i-Akkermansia muciniphila inciphisa ukukhuluphala ngokulawula i-bile acid metabolism ngokusebenzisa i-indole - 3 - lactic acid (ILA)/m6A/CYP8B1 indlela yokusayina. I-Quercetin ingathuthukisa ukudla okunamafutha amaningi - ukukhuluphala okudalwe kanye nokuphazamiseka kwe-metabolic okuhlobene, imise kabusha isakhiwo se-microbiota, futhi ikhulise ukuchichima kwe-Akkermansia muciniphila. Le bhaktheriya inothisa futhi ikhiqize i-ILA eningi, ephakamisa - elawula ukuvezwa kwe-CYP8B1 ngendlela ye-FTO/m6A/YTHDF2, ithuthukisa ukuguqulwa kwe-cholesterol ibe i-cholic acid, bese yenza kusebenze isamukeli se-farnesoid X kuzicubu ze-adipose ukuze kuvinjwe ukunqwabelana kwe-lipid.