● Yini i-urolixin a
I-Urolithin a Ama-ellagitann atholakala kabanzi ekudleni okufana namapomegranati, ama-sitrobheli, ama-raspberries, ama-walnuts, newayini elibomvu. Lapho abantu besebenzisa lokhu kudla, ama-ellagitannins aguqulwa abe ngurolithi a ngama-microbial abantu athile emathunjini.
● Izakhiwo eziyisisekelo ze-urolithin a
Igama lesiNgisi: Urolithin a
Inombolo ye-CAS: 1143-70-0
Ifomu lama-molecular. : C₁₃h₈o₄
Isisindo samangqamuzana: 228.2
Ukubukeka: Uphuzi ophuzi noma okhanyayo okhanyayo ophuzi
● Ukusebenza kwe-Biolixin kanye nokusebenza kwe-Urolixin a
1:Umphumela wokulwa nokuguga
Ngcono umsebenzi we-mitochondrial: Urolithin A ungavuselela uMitophagy, asuse ukusula i-mitochondria elonakalisiwe, ukukhuthaza ukukhiqizwa kwamaseli ama-cell kanye nokuthola amandla okugula kwamaseli.
2:Umphumela we-neuroprotactive
Yehlisa i-Neuroinflation: U-Urolitin A angawela umgoqo wegazi-ubuchopho, ukunciphisa ama-ampyloid beta (aby) kanye ne-tau amaprotheni autopharion, uthuthumela umsebenzi we-mutochond.Izifo zesifo se-mitochon.impred.iths. Umsebenzi we-Ololy kumodeli amagundane.
3:Ukuvikelwa kwemisipha
Khulisa Amandla Emisipha nokukhuthazela: I-UROLIXIN A ingathuthukisa impilo yemisipha, ukukhulisa amandla emisipha nokukhuthazela, futhi ineqhaza elingase libe ne-asebekhulile noma i-mustelity reffect ngenxa yezifo eziphathelene nokuzivocavoca nokukhuthaza ukululama kwemisipha ngenxa yokuvuselelwa kwemisipha.
4:Umphumela wokulwa nokuvuvukala
Ukuvinjwa kwezinto zokuvuvukala: Urolithin A kungavimba ukukhiqizwa nokukhishwa kwezinto zokuvuvukala ezinjenge-IL-6 ne-TNF-α, futhi kunciphise ukulungiswa kwe-NFAMLatory
5:I-Antioxidation
I-Scavengeling Free Radicals: I-UROLIXIN A inamandla okususa ngokuqondile ama-radicals wamahhala futhi inciphise ukulimala kwe-oxidative amaseli ama-antioxidant defense ngama-enzyme ahlukahlukene ahlukahlukene njenge-enzyme ehlukahlukene efana ne-glutathione peroxidase kanye ne-superoxide dismulase.
6:Umphumela we-antitumoren
Ukuvinjwa kwe-Tumor Cell Preliferation: URolixin A kungavimba ukwanda, ukuhlasela kanye ne-metastasis yomdlavuza we-prostate, umdlavuza we-colon namanye amaseli e-tumor.
7:Ngcono izifo ze-metabolic
Ukulawulwa koshukela wegazi kanye ne-lipid yegazi: Urolithin akwazi ukulawula indlela enhle ye-metabolic futhi uhlele indima enhle ekwenzeni ushukela wegazi kanye ne-browning browning, ngokuvimbela ukunqwabelana okunsundu, ngokuvimbela ukunqwabelana kwamafutha okubangelwa ukudla.
8:Thuthukisa isifo sezinso
Ukunciphisa ukulimala kwezinso: U-Urolixin A kunganciphisa ukulimala kwezinso ngokwenza kusebenze i-mitochondrial autopharicy yamaseli ezinso, ukunciphisa ukwanda kwe-fibrocyte noma ukunciphisa ukuncishiswa kwezicubu zefibha ukunciphisa ukuthuthukiswa kwenqubo ye-fibrosis.
● ithemba lesicelo se-urolithin a
1:Ucwaningo lwezidakamizwa nentuthuko
I-Urolixin A iyithagethi ethandwayo yokulwa nokuguga, ukuthuthukiswa kwezidakamizwa, okulwa nezidakamizwa ngenxa yemisebenzi yayo ehlukahlukene.Ikhona, izikhungo eziningi zokucwaninga namabhizinisi aseqalile ukufundela izidakamizwa ze-urolixin a, ngethemba lokuthuthukisa izidakamizwa ezisebenzayo neziphephile.
2:Ukucwaninga Kwezimonyo Nentuthuko
Imiphumela ye-antioxidant ne-anti-ukuvuvukala ye-urolixin a yenza amathemba wohlelo lokusebenza abanzi emkhakheni wezimonyo- ama-cosmetics a, izimonyo angathuthukisa imiphumela yokulwa nokuguga futhi athuthukise isimo sesikhumba.
3:Ukucwaninga kokudla nentuthuko
I-UROLIXIN A inenani lesicelo sendawo yokudla ngenxa yemisebenzi yayo ehlukahlukene yemvelo.Bungeza ukudla okucebile kwe-ellagitannin noma i-urolithin izithasiselo, ukudla kungathuthukisa izinzuzo zezempilo futhi kuhlangane nesidingo sabathengi sokudla okunempilo.
Ukuxhumana: Judy Guo
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Isikhathi sePosi: Mar-27-2025